{"id":3120,"date":"2023-07-21T13:39:02","date_gmt":"2023-07-21T04:39:02","guid":{"rendered":"http:\/\/jmc.brc.riken.jp\/ja\/?p=3120"},"modified":"2026-04-16T16:31:33","modified_gmt":"2026-04-16T07:31:33","slug":"publications","status":"publish","type":"page","link":"http:\/\/jmc.brc.riken.jp\/ja\/lab\/publications","title":{"rendered":"\u7814\u7a76\u696d\u7e3e"},"content":{"rendered":"
\"\u8ad6\u6587\u57f7\u7b46\"<\/div>\n

\u30c8\u30c3\u30d7\u30da\u30fc\u30b8<\/a> > \u7814\u7a76\u5ba4<\/a> > \u7814\u7a76\u696d\u7e3e<\/span><\/p>\n\n\n\n

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\u7814\u7a76\u696d\u7e3e<\/h2>\n\n\n\n

2026<\/span><\/h4>\n\n\n\n

Takeda Y., Kuramoto-Ahuja T., Yonei-Tamura S., Shibuya H.<\/span>, Tamura M.<\/span>, Uesaka M., Tamura K. Ontogenic Development of the Acrocoracoid Process Responsible for the Evolution of Avian Flapping Flight. Zoolog. Sci.<\/em><\/strong> 2026, 43: 61\u201371. (doi: 10.2108\/zs250113)<\/p>\n\n\n\n

Tanaka N., Miura K., Ozaki A., Kozawa Y.<\/span>, Tamura M.<\/span>, Ogura A., Matoba S. Quantitative dissection of sexual dimorphism in mice through Y-linked gene knockouts and multivariate phenotyping. Sci Rep.<\/em><\/strong> 2026, 6;16:2190. (doi: 10.1038\/s41598-025-33814-w)<\/p>\n\n\n\n

2025<\/span><\/h4>\n\n\n\n

Takada T., Miyazawa H., Yamagata M., Tamura M.<\/span>, Yoshiki A., Toyoda A., Noguchi H., Masuya H. MoG+3.0: expanded structural variant visualization and integration of genomic data from five newly analyzed mouse strains. Mamm. Genome<\/em><\/strong> 2025. (doi: 10.1007\/s00335-025-10168-2)<\/p>\n\n\n\n

Ogawa E., Oikawa T., Ayabe S., Miwa T., Mizuno S., Nozaki T., Kosaki K., Yoshiki A., Tamura M.<\/span>, Takenouchi T. Haploinsufficiency of Runx2 restores the cranial sutures in a mouse model of Pdgfrb-related craniosynostosis. Hum. Mol. Genet.<\/em><\/strong> 2025, 34: 1856\u20131864. (doi: 10.1093\/hmg\/ddaf148)<\/p>\n\n\n\n

Ogonuki N., Hino T., Fujiwara Y., Osawa Y., Mizuno S., Sugiyama F., Kunieda T., Otsuki J., Oura S., Furuse T.<\/span>, Okada Y., Tamura M.<\/span>, de la Casa-Esperon E., Ikawa M., Inoue K., Ogura A. Spermatocyte injection into meiotic oocytes rescues diplotene, but not pachytene, arrest in azoospermic mutant mice. Human Reproduction Open<\/em><\/strong> 2025, hoaf067. (doi: 10.1093\/hropen\/hoaf067)<\/p>\n\n\n\n

Rahmawati NY., Dinh TT., Oikawa T.<\/span>, Shinogi A.<\/span>, Ikeda K.<\/span>, Kadota M., Tamura M.<\/span>, Amano T., Yoshiki A. Luminescent mouse model of endometriosis: three-dimensional morphology of lesions and cytokine profiles. Exp. Anim.<\/em><\/strong> 2025, 74: 419\u2013428. (doi: 10.1538\/expanim.25-0044)<\/p>\n\n\n\n

Hang A., Shao A., Shea M., Roux MJ., Imai-Leonard DM., Adams DJ., Amano T., Amarie OV., Berberovic Z., Bour R., Bower L., Leonard BC., Brown SD., Cho SY., Clementson-Mobbs S., D'Souza AJ., Dickinson M., Eskandarian M., Flenniken AM., Fuchs H., Gailus-Durner V., Heaney J., H\u00e9rault Y., de Angelis MH., Hsu C., Jin S.<\/span>, Joynson R., Kang YK., Kim H., Masuya H., Nam K., Noh H., Nutter LM., Palkova M., Prochazka J., Raishbrook MJ., Riet F., Salazar J., Seavitt JR., Sedlacek R., Selloum M., Seo KY., Seong JK., Shin H., Shiroishi T., Sorg T., Stewart M., Tamura M.<\/span>, Tolentino H., Udensi U., Wells S., Wurst W., Yoshiki A., Meziane H., Yiu GC., Sieving PA., Lanoue L., Lloyd KC., McKerlie C., Moshiri A., Consortium, f. t. Ocular Phenotyping of Knockout Mice Identifies Genes Associated With Late Adult Retinal Phenotypes. Invest. Ophthalmol. Visual Sci.<\/em><\/strong> 2025, 66, 64. (doi: 10.1167\/iovs.66.6.64)<\/p>\n\n\n\n

Briere A., Vo P., Yang B., Adams D., Amano T., Amarie O., Berberovic Z., Bower L., Brown SD., Burrill S., Cho SY., Clementson-Mobbs S., D'souza A., Eskandarian M., Flenniken AM., Fuchs H., Gailus-Durner V., H\u00e9rault Y., de Angelis MH., Jin S.<\/span>, Joynson R., Kang YK., Kim H., Masuya H., Meziane H., Nam K., Noh H., Nutter LM., Palkova M., Prochazka J., Raishbrook MJ., Riet F., Salazar J., Sedlacek R., Selloum M., Seo KY., Seong JK., Shin H., Shiroishi T., Stewart M., Svenson K., Tamura M.<\/span>, Tolentino H., Wells S., Wurst W., Yoshiki A., Lanoue L., Lloyd KC., Leonard BC., Roux MJ., McKerlie C., Moshiri A., Consortium fT. Systematic Ocular Phenotyping of Knockout Mouse Lines Identifies Genes Associated With Age-Related Corneal Dystrophies. Invest. Ophthalmol. Visual Sci.<\/em><\/strong> 2025, 66, 7. (doi: 10.1167\/iovs.66.5.7)<\/p>\n\n\n\n

Liu S., Xu L., Kashima M., Narumi R., Takahata Y., Nakamura E., Shibuya H.<\/span>, Tamura M.<\/span>, Shida Y., Inubushi T., Nukada Y., Miyazawa M., Hata K., Nishimura R., Yamashiro T., Tasaki J., Kurosaka H. Expression analysis of genes including Zfhx4 in mice and zebrafish reveals a temporospatial conserved molecular basis underlying craniofacial development. Dev. Dyn.<\/em><\/strong> 2024, 254: 257\u2013271. (doi: 10.1002\/dvdy.740)<\/p>\n\n\n\n

Goto T., Tanabe R., Shibuya H.<\/span>, Tamura M.<\/span>, Nomura S. Visualization of Small Vessels by Micro-Computed Tomography Using Titanium Dioxide Nanoparticles as a Novel Contrast Agent. IntJ. Biomed. Imaging<\/em><\/strong> 2025, 6688558. (doi: 10.1155\/ijbi\/6688558)<\/p>\n\n\n\n

Vo P., Imai-Leonard DM., Yang B., Briere A., Shao A., Casanova MI., Adams D., Amano T., Amarie O., Berberovic Z., Bower L., Braun R., Brown S., Burrill S., Cho SY., Clementson-Mobbs S., D\u2019Souza A., Dickinson M., Eskandarian M., Flenniken AM., Fuchs H., Gailus-Durner V., Heaney J., H\u00e9rault Y., Angelis MH., Hsu C., Jin S.<\/span>, Joynson R., Kang YK., Kim H., Masuya H., Meziane H., Murray S., Nam K., Noh H., Nutter LM., Palkova M., Prochazka J., Raishbrook MJ., Riet F., Ryan J., Salazar J., Seavey Z., Seavitt JR., Sedlacek R., Selloum M., Seo KY., Seong JK., Shin H., Shiroishi T., Stewart M., Svenson K., Tamura M.<\/span>, Tolentino H., Udensi U., Wells S., White J., Willett A., Wotton J., Wurst W., Yoshiki A., Lanoue L., Lloyd KC., Leonard BC., Roux MJ., McKerlie C., Moshiri A. Systematic ocular phenotyping of 8,707 knockout mouse lines identifies genes associated with abnormal corneal phenotypes. BMC Genomics<\/em><\/strong> 2025, 26, 48. (doi: 10.1186\/s12864-025-11222-8)<\/p>\n\n\n\n

2024<\/span><\/h4>\n\n\n\n

Nagaretnam I., Kakimoto Y., Yoneshige A., Takeuchi F., Sakimura T., Sato K., Osaki Y., Ishii Y., Ozaki A., Tamura M.<\/span>, Hamada M., Shigeoka T., Ito A., Ishida Y. Granulomatous inflammatory responses are elicited in the liver of PD-1 knockout mice by de novo genome mutagenesis. Discovery Immunology<\/em><\/strong> 2024, 4, kyae018. (doi: 10.1093\/discim\/kyae018)<\/p>\n\n\n\n

Kanatsu-Shinohara M., Morimoto H., Liu T., Tamura M.<\/span>, Shinohara T. Sendai virus-mediated RNA delivery restores fertility to congenital and chemotherapy-induced infertile female mice. PNAS Nexus<\/em><\/strong> 2024, 3, pgae375. (doi: 10.1093\/pnasnexus\/pgae375)<\/p>\n\n\n\n

Hirose M., Inoue K., Matoba S., Tatebe T., Tokita S., Dodo Y., Tomishima T., Hasegawa A., Honda A., Ozaki M.<\/span>, Shinogi A.<\/span>, Yanagisawa R.<\/span>, Fauzi M., Murakami T., Inagaki N., Tamura M.<\/span>, Ogura A. Disruption of insulin receptor substrate 2 (IRS2) causes non-obese type 2 diabetes with \u03b2-cell dysfunction in the golden (Syrian) hamster. Sci. Rep.<\/em><\/strong> 2024, 14, 17450. (doi: 10.1038\/s41598-024-67513-9)<\/p>\n\n\n\n

Hagihara H., Shoji H., Hattori S., Sala G., Takamiya Y., Tanaka M., Ihara M., Shibutani M., Hatada I., Hori K., Hoshino M., Nakao A., Mori Y., Okabe S., Matsushita M., Urbach A., Katayama Y., Matsumoto A., Nakayama KI., Katori S., Sato T., Iwasato T., Nakamura H., Goshima Y., Raveau M., Tatsukawa T., Yamakawa K., Takahashi N., Kasai H., Inazawa J., Nobuhisa I., Kagawa T., Taga T., Darwish M., Nishizono H., Takao K., Sapkota K., Nakazawa K., Takagi T., Fujisawa H., Sugimura Y., Yamanishi K., Rajagopal L., Hannah ND., Meltzer HY., Yamamoto T., Wakatsuki S., Araki T., Tabuchi K., Numakawa T., Kunugi H., Huang FL., Hayata-Takano A., Hashimoto H., Tamada K., Takumi T., Kasahara T., Kato T., Graef IA., Crabtree GR., Asaoka N., Hatakama H., Kaneko S., Kohno T., Hattori M., Hoshiba Y., Miyake R., Obi-Nagata K., Hayashi-Takagi A., Becker LJ., Yalcin I., Hagino Y., Kotajima-Murakami H., Moriya Y., Ikeda K., Kim H., Kaang B., Otabi H., Yoshida Y., Toyoda A., Komiyama NH., Grant SG., Ida-Eto M., Narita M., Matsumoto K., Okuda-Ashitaka E., Ohmori I., Shimada T., Yamagata K., Ageta H., Tsuchida K., Inokuchi K., Sassa T., Kihara A., Fukasawa M., Usuda N., Katano T., Tanaka T., Yoshihara Y., Igarashi M., Hayashi T., Ishikawa K., Yamamoto S., Nishimura N., Nakada K., Hirotsune S., Egawa K., Higashisaka K., Tsutsumi Y., Nishihara S., Sugo N., Yagi T., Ueno N., Yamamoto T., Kubo Y., Ohashi R., Shiina N., Shimizu K., Higo-Yamamoto S., Oishi K., Mori H., Furuse T.<\/span>, Tamura M.<\/span>, Shirakawa H., Sato DX., Inoue YU., Inoue T., Komine Y., Yamamori T., Sakimura K., Miyakawa T. Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment. eLife<\/em><\/strong> 2024, 12. (doi: 10.7554\/elife.89376)<\/p>\n\n\n\n

Kawashima H., Nishimata S., Shinji S., Morishima Y., Tsutsumi N., Kashiwagi K., Amano T., Tamura M.<\/span>, Ayabe S., Nakashima K. Three Siblings with Aarskog Scott Syndrome Together with Mental Retardation and Giant Megacolon. Global Journal of Pediatrics <\/strong><\/em>2024, 2.<\/p>\n\n\n\n

2023<\/span><\/h4>\n\n\n\n

Son R., Yamazawa K., Oguchi A., Suga M., Tamura M.<\/span>, Yanagita M., Murakawa Y., Kume S. Morphomics via next-generation electron microscopy. J Mol Cell Biol<\/em><\/strong> 2023: mjad081. (doi: 10.1093\/jmcb\/mjad081)<\/p>\n\n\n\n

Yamada M., Nitta Y., Uehara T., Suzuki H., Miya F., Takenouchi T., Tamura M.<\/span>, Ayabe S., Yoshiki A., Maeno A., Saga Y., Furuse T.<\/span>, Yamada I.<\/span>, Okamoto N., Kosaki K., Sugie A. Heterozygous loss-of-function DHX9 variants are associated with neurodevelopmental disorders: Human genetic and experimental evidences. Eur J Med Genet<\/em><\/strong> 2023, 66: 104804. (doi: 10.1016\/j.ejmg.2023.104804)<\/p>\n\n\n\n

Oestereicher MA., Wotton JM., Ayabe S., About GB., Cheng TK., Choi JH., Clary D., Dew EM., Elfertak L., Guimond A., Mashhadi HH., Heaney JD., Kelsey L., Keskivali-Bond P., Gomez FL., Marschall S., McFarland M., Meziane H., Fuentes VM., Nam KH., Nichtov\u00e1 Z., Pimm D., Bower L., Prochazka J., Rozman J., Santos L., Stewart M., Tanaka N., Ward CS., Willett AME., Wilson R., Braun RE., Dickinson ME., Flenniken AM., Herault Y., Lloyd KCK., Mallon AM., McKerlie C., Murray SA., Nutter LMJ., Sedlacek R., Seong JK., Sorg T., Tamura M.<\/span>, Wells S., Schneltzer E., Fuchs H., Gailus-Durner V., Angelis MH., White JK., Spielmann N. Comprehensive ECG reference intervals in C57BL\/6N substrains provide a generalizable guide for cardiac electrophysiology studies in mice. Mammalian Genome<\/em><\/strong> 2023, 34: 180-199. (doi: 10.1007\/s00335-023-09995-y)<\/p>\n\n\n\n

Lin CW., Ellegood J., Tamada K., Miura I., Konda M., Takeshita K., Atarashi K., Lerch JP., Wakana S., McHugh TJ., Takumi T. An old model with new insights: endogenous retroviruses drive the evolvement toward ASD susceptibility and hijack transcription machinery during development. Molecular Psychiatry<\/em><\/strong> 2023, 28: 1932-1945. (doi: 10.1038\/s41380-023-01999-z)<\/p>\n\n\n\n

Sato Y., Tamura M.<\/span>, Yanagita M. Tertiary lymphoid tissues: a regional hub for kidney inflammation. Nephrol Dial Transplant.<\/em><\/strong> 2023, 38: 26-33. (doi: 10.1093\/ndt\/gfab212)<\/p>\n\n\n\n

2022<\/span><\/h4>\n\n\n\n

Kunishima N., Takeda Y., Hirose R., Kume S., Maeda M., Oguchi A., Yanagita M., Shibuya H.<\/span>, Tamura M.<\/span>, Kataoka Y., Murakawa Y., Ito K., Omote K. Compact laboratory-based X-ray microscope enabling nondestructive 3D structure acquisition of mouse nephron with high speed and better user accessibility. Microscopy (Oxford Journals)<\/em><\/strong> 2022, 71: 315-323. (doi: 10.1093\/jmicro\/dfac033)<\/p>\n\n\n\n

Mizumoto T., Yoshizawa T., Sato Y., Ito T., Tsuyama T., Satoh A., Araki S., Tsujita K., Tamura M.<\/span>, Oike Y., Yamagata K. SIRT7 Deficiency Protects against Aging-Associated Glucose Intolerance and Extends Lifespan in Male Mice. Cells<\/em><\/strong> 2022, 11: 3609. (doi: 10.3390\/cells11223609)<\/p>\n\n\n\n

Miyasaka Y., Okuda K., Miura I.<\/span>, Motegi H., Wakana S., Ohno T. A novel ENU-induced Cpox mutation causes microcytic hypochromic anemia in mice. Experimental Animals<\/em><\/strong> 2022, 71: 433-441. (doi: 10.1538\/expanim.22-0032)<\/p>\n\n\n\n

Sato Y., Tsuyusaki M., Takahashi-Iwanaga H., Fujisawa R., Masamune A., Hamada S., Matsumoto R., Tanaka Y., Kakuta Y., Yamaguchi-Kabata Y., Furuse T.<\/span>, Wakana S., Shimura T., Kobayashi R., Shinoda Y., Goitsuka R., Maezawa S., Sadakata T., Sano Y., Furuichi T. Loss of CAPS2\/Cadps2 leads to exocrine pancreatic cell injury and intracellular accumulation of secretory granules in mice. Front Mol Biosci.<\/em><\/strong> 2022, 9: 1040237. (doi: 10.3389\/fmolb.2022.1040237)<\/p>\n\n\n\n

Watanabe C., Shibuya H.<\/span>, Ichiyama Y., Okamura E., Tsukiyama-Fujii S., Tsukiyama T., Matsumoto S., Matsushita J., Azami T., Kubota Y., Ohji M., Sugiyama F., Takahashi S., Mizuno S., Tamura M.<\/span>, Mizutani K., Ema M. Essential Roles of Exocyst Complex Component 3-like 2 on Cardiovascular Development in Mice. Life (Basel)<\/em><\/strong> 2022, 12: 1730. (doi: 10.3390\/life12111730)<\/p>\n\n\n\n

Hara T., Yamada I.<\/span>, Ohashi T., Tamura M.<\/span>, Hijikata A., Watanabe T., Gao M., Ito K., Kawamata S., Azuma S., Yoshigai E., Sumiyoshi Y., Yasuhiro N., Ohara O., Santos HGD., Fukada T. Role of Scl39a13\/ZIP13 in cardiovascular homeostasis. PLOS ONE<\/em><\/strong> 2022, 17: e0276452. (doi: 10.1371\/journal.pone.0276452)<\/p>\n\n\n\n

Uemura M., Furuse T.<\/span>, Yamada I.<\/span>, Kushida T.<\/span>, Abe T., Imai K., Nagao S., Kudoh M., Yoshizawa K., Tamura M.<\/span>, Kiyonari H., Wakana S., Hirano S. Deficiency of protocadherin 9 leads to reduction in positive emotional behaviour. Scientific Reports<\/em><\/strong> 2022, 12: 11933. (doi: 10.1038\/s41598-022-16106-5)<\/p>\n\n\n\n

Hashimoto D., Fujimoto K., Morioka S., Ayabe S., Kataoka T., Fukumura R., Ueda Y., Kajimoto M., Hyuga T., Suzuki K., Hara I., Asamura S., Wakana S., Yoshiki A., Gondo Y., Tamura M.<\/span>, Sasaki T., Yamada G. Establishment of mouse line showing inducible priapism-like phenotypes. Reprod Med Biol.<\/em><\/strong> 2022, 21: e12472. (doi: 10.1002\/rmb2.12472)<\/p>\n\n\n\n

Miura I.<\/span>, Kikkawa Y., Yasuda SP., Shinogi A.<\/span>, Usuda D., Kumar V., Takahashi JS., Tamura M.<\/span>, Masuya H., Wakana S. Characterization of single nucleotide polymorphisms for a forward genetics approach using genetic crosses in C57BL\/6 and BALB\/c substrains of mice. Experimental Animals<\/em><\/strong> 2022, 71: 240-251. (doi: 10.1538\/expanim.21-0181)<\/p>\n\n\n\n

Hirata T., Kobayashi A., Furuse T.<\/span>, Yamada I.<\/span>, Tamura M.<\/span>, Tomita H., Tokoro Y., Ninomiya A., Fujihara Y., Ikawa M., Maeda Y., Murakami Y., Kizuka Y., Kinoshita T. Loss of the N-acetylgalactosamine side chain of the GPI-anchor impairs bone formation and brain functions and accelerates the prion disease pathology. J Biol Chem.<\/em><\/strong> 2022 , 298: 101720. (doi: 10.1016\/j.jbc.2022.101720)<\/p>\n\n\n\n

Mizuno-Iijima S., Nakashiba T., Ayabe S., Nakata H., Ike F., Hiraiwa N., Mochida K., Ogura A., Masuya H., Kawamoto S., Tamura M.<\/span>, Obata Y., Shiroishi T., Yoshiki A. Mouse resources at the RIKEN BioResource Research Center and the National BioResource Project core facility in Japan. Mammalian Genome<\/em><\/strong> 2022, 33: 181-191. (doi: 10.1007\/s00335-021-09916-x)<\/p>\n\n\n\n

2021<\/span><\/h4>\n\n\n\n

Nakano T., Aochi H., Hirasaki M., Takenaka Y., Fujita K., Tamura M.<\/span>, Soma H., Kamezawa H., Koizumi T., Shibuya H.<\/span>, Inomata R., Okuda A., Murakoshi T., Shimada A. and Inoue I. Effects of Ppar\u03b31 deletion on late-stage murine embryogenesis and cells that undergo endocycle. Developmental Biology<\/em><\/strong> 2021, 478: 222-235. (doi: 10.1016\/j.ydbio.2021.07.003)<\/p>\n\n\n\n

Zhang C., Clough SJ., Adamah-Biassi EB., Sveinsson MH., Hutchinson AJ., Miura I.<\/span>, Furuse T.<\/span>, Wakana S., Matsumoto YK., Okanoya K., Hudson RL., Kato T., Dubocovich ML., Kasahara T. Impact of endogenous melatonin on rhythmic behaviors, reproduction, and survival revealed in melatonin-proficient C57BL\/6J congenic mice. Journal of Pineal Research<\/em><\/strong> 2021, 71: e12748. (doi: 10.1111\/jpi.12748)<\/p>\n\n\n\n

Birling MC., Yoshiki A., Adams D., Ayabe S., Beaudet AL., Bottomley J., Bradley A., Brown SDM., Burger A., Bushell W., Chiani F., Christou S., Codner GF., DeMayo FJ., Dickinson ME., Doe B., Donahue LR., Fray MD., Gambadoro A., Gertsenstein M., Gomez-Segura A., Goodwin LO., Heaney JD., Herault Y., Hrabe de Angelis M., Justice MJ., King RE., Kuhn R., Lee H., Lee YJ., Lloyd KCK., Lorenzo I., Mallon AM., McKerlie C., Meehan TF., Nutter LMJ., Oh GT., Pavlovic G., Ramirez-Solis R., Rosen B., Ryder EJ., Santos LA., Schick J., Seavitt JR., Seong JK., Skarnes WC., Steel K., Tamura M.<\/span>, Tocchini-Valentini GP, Wardle-jones H., Wattenhofer-donze M., Wells S., Willis BJ., Wood JA., Wurst W., The International Mouse Phenotyping Consortium, Teboul L. and Murray SA. A resource of targeted mutant mouse lines for 5,061 genes. Nature Genetics<\/em><\/strong> 2021, 53: 416-419. (doi: 10.1038\/s41588-021-00825-y)<\/p>\n\n\n\n

2020<\/span><\/h4>\n\n\n\n

Horiai M., Otsuka A., Hidema S., Hiraoka Y., Hayashi R., Miyazaki S., Furuse T.<\/span>, Mizukami H., Teruyama R., Tamura M.<\/span>, Bito H., Maejima Y., Shimomura K., and Nishimori K. Targeting oxytocin receptor (Oxtr)-expressing neurons in the lateral septum to restore social novelty in autism spectrum disorder mouse models. Scientific Reports<\/em><\/strong> 2020, 10: 22173. (doi: 10.1038\/s41598-020-79109-0)<\/p>\n\n\n\n

Tanaka S., Ise W., Inoue T., Ito A., Ono C., Shima Y., Sakakibara S., Nakayama M., Fujii K., Miura I.<\/span>, Sharif J., Koseki H., Koni PA., Raman I., Li QZ., Kubo M., Fujiki K., Nakato R., Shirahige K., Araki H., Miura F., Ito T., Kawakami E., Baba Y. and Kurosaki T. Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity. Nature Immunology<\/em><\/strong> 2020, 21: 950-961. (doi: 10.1038\/s41590-020-0700-y)<\/p>\n\n\n\n

Matsumura K., Seiriki K., Okada S., Nagase M., Ayabe S., Yamada I.<\/span>, Furuse T.<\/span>, Shibuya H.<\/span>, Yasuda Y., Yamamori H., Fujimoto M., Nagayasu K., Yamamoto K., Kitagawa K., Miura H., Gotoda-Nishimura N., Igarashi H., Hayashida M., Baba M., Kondo M., Hasebe S., Ueshima K., Kasai A., Ago Y., Hayata-Takano A., Shintani N., Iguchi T., Sato M., Yamaguchi M., Tamura M.<\/span>, Wakana S., Yoshiki A., Watabe A., Okano H., Takuma K., Hashimoto R., Hashimoto H. and Nakazawa T. Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes. Nature Communications<\/em><\/strong> 2020, 11: 859. (doi: 10.1038\/s41467-020-14697-z)<\/p>\n\n\n\n

Terumitsu-Tsujita M., Kitaura H., Miura I.<\/span>, Kiyama Y., Goto F., Muraki Y., Ominato S., Hara N., Simankova A., Bizen N., Kashiwagi K., Ito T., Toyoshima Y., Kakita A., Manabe T., Wakana S., Takebayashi H. and Igarashi H. Glial pathology in a novel spontaneous mutant mouse of the Eif2b5 gene: a vanishing white matter disease model. Journal of Neurochemistry<\/em><\/strong> 2020, 154: 25-40. (doi: 10.1111\/jnc.14887)<\/p>\n\n\n\n

2019<\/span><\/h4>\n\n\n\n

Haselimashhadi H., Mason J., Munoz-Fuentes V., Lopez-Gomez F., Babalola K., Acar E., Kuma V., White J., Flenniken A., King R., Straiton E., Seavitt JR., Gaspero A., Garza A., Christiansen A., Hsu CW., Reynolds C., Lanza D., Lorenzo I., Green J., Gallegos J., Bohat R., Samaco R., Veeraragavan S., Kim JK., Miller G., Fuchs H., Garrett L., Becker L., Kang YK., Clary D., Soo Y., Tamura M.<\/span>, Tanaka N., Kyoung DS., Bezginov A., Bou About G., Champy MF., Vasseur L., Leblanc S., Meziane H., Selloum M., Reilly P., Spielmann N., Maier H., Gailus-Durner V., Sorg T., Masuya H., Obata Y., Heaney J., Dickinson M., Wurst W., Tocchini-Valentini G., Lloyd KCK., McKerlie C., Seong JK., H\u00e9rault Y., Hrab\u00e9 de Angelis M., Brown S., Smedley D., Flicek P., Mallon AM., Parkinson H. and Meehan T. Soft Windowing Application to Improve Analysis of High-throughput Phenotyping Data. Bioinformatics<\/em><\/strong> 2019, btz744, (doi: org\/10.1093\/bioinformatics\/btz744)<\/p>\n\n\n\n

Furuse T.<\/span>, Mizuma H., Hirose Y., Kushida T.<\/span>, Yamada I.<\/span>, Miura I., Masuya H., Funato H., Yanagisawa M., Onoe H. and Wakana S. A new mouse model of GLUT1 deficiency syndrome exhibits abnormal sleep-wake patterns and alterations of glucose kinetics in the brain. Disease Models & Mechanisms<\/em><\/strong> 2019, 12: dmm038828. (doi: 10.1242\/dmm.038828)<\/p>\n\n\n\n

Kim K., Suzuki A., Kojima H., Kawamura M., Miya K., Abe M., Yamada I.<\/span>, Furuse T.<\/span>, Wakana S., Sakimura K. and Hayashi Y. Autophosphorylation of F-actin binding domain of CaMKII\u03b2 is required for fear learning. Neurobiol Learn Mem.<\/em><\/strong> 2019, 157: 86-95. (doi: 10.1016\/j.nlm.2018.12.003)<\/p>\n\n\n\n

2018<\/span><\/h4>\n\n\n\n

Kishimoto K., Tamura M.<\/span>, Nishita M., Minami Y., Yamaoka A., Abe T., Shigeta M. and Morimoto M. Synchronized mesenchymal cell polarization and differentiation shape the formation of the murine trachea and esophagus. Nature Communications<\/em><\/strong> 2018, 9: 2816. (doi: 10.1038\/s41467-018-05189-2)<\/p>\n\n\n\n

Takahashi M., Tamura M.<\/span>, Sato S. and Kawakami K. Mice doubly deficient in Six4 and Six5 show ventral body wall defects reproducing human omphalocele. Disease Models & Mechanisms<\/em><\/strong> 2018, 11: dmm.034611. (doi: 10.1242\/dmm.034611)<\/p>\n\n\n\n

Shibuya H.<\/span>, Watanabe R., Maeno A., Ichimura K., Tamura M.<\/span>, Wakana S., Shiroishi T., Ohba K., Takeda K., Tomita H., Shibahara S. and Yamamoto H. Melanocytes contribute to the vasculature of the choroid. Genes & Genetic Systems<\/em><\/strong> 2018, 93: 51-58. (doi: 10.1266\/ggs.17-00058)<\/p>\n\n\n\n

Rozman J., Rathkolb B., Oestereicher MA., Sch\u00fctt C., Ravindranath AC., Leuchtenberger S., Sharma S., Kistler M., Willersh\u00e4user M., Brommage R., Meehan TF., Mason J., Haselimashhadi H., The International Mouse Phenotyping Consortium<\/span>, Hough T., Mallon AM., Wells S., Santos L., Lelliott CJ., White JK., Sorg T., Champy MF., Bower LR., Reynolds CL., Flenniken AM., Murray SA., Nutter LMJ., Svenson KL., West D., Tocchini-Valentini GP., Beaudet AL., Bosch F., Braun RB., Dobbie MS., Gao X., Herault Y., Moshiri A., Moore BA., Kent LKC., McKerlie C., Masuya H., Tanaka N., Flicek P., Parkinson HE., Sedlacek R., Seong JK., Wang CL., Moore M., Brown SD., Tsch\u00f6p MH., Wurst W., Klingenspor M., Wolf E., Beckers J., Machicao F., Peter A., Staiger H., H\u00e4ring HU., Grallert H., Campillos M., Maier H., Fuchs H., Gailus-Durner V., Werner T. and Hrabe de Angelis M. Identification of genetic elements in metabolism by high-throughput mouse phenotyping. Nature Communications<\/em><\/strong> 2018, 9: 288. (doi: 10.1038\/s41467-017-01995-2)<\/p>\n\n\n\n

Moore BA., Leonard BC., Sebbag L., Edwards SG., Cooper A., Imai DM., Straiton E., Santos L., Reilly C., Griffey SM., Bower L., Clary D., Mason J., Roux MJ., Meziane H., Herault Y., The International Mouse Phenotyping Consortium<\/span>, McKerlie C., Flenniken AM., Nutter LMJ., Berberovic Z., Owen C., Newbigging S., Adissu H., Eskandarian M., Hsu CW., Kalaga S., Udensi U., Asomugha C., Bohat R., Gallegos JJ., Seavitt JR., Heaney JD., Beaudet AL., Dickinson ME., Justice MJ., Philip V., Kumar V., Svenson KL., Braun RE., Wells S., Cater H., Stewart M., Clementson-Mobbs S., Joynson R., Gao X., Suzuki T., Wakana S., Smedley D., Seong JK., Tocchini-Valentini G., Moore M., Fletcher C., Karp N., Ramirez-Solis R., White JK., Hrabe de Angelis M, Wurst W., Thomasy SM., Flicek P., Parkinson H., Brown SDM., Meehan TF., Nishina PM., Murray SA., Krebs MP., Mallon AM., Lloyd KCK., Murphy CJ. and Moshiri A. Identification of genes required for eye development by high-throughput screening of mouse knockouts. Communications Biology<\/em><\/strong> 2018, 1: 236. (doi: 10.1038\/s42003-018-0226-0)<\/p>\n\n\n\n

Shimazu T., Furuse T.<\/span>, Balan S., Yamada I.<\/span>, Okuno S., Iwanari H., Suzuki T., Hamakubo T., Dohmae N., Yoshikawa T., Wakana S. and Shinkai Y. Role of METTL20 in regulating \u03b2-oxidation and heat production in mice under fasting or ketogenic conditions. Scientific Reports<\/em><\/strong> 2018 8: 1179. (doi: 10.1038\/s41598-018-19615-4)<\/p>\n\n\n\n

Gotoh H., Miura I.<\/span> and Wakana S. Genetic mapping of a male factor subfertility locus on mouse chromosome 4. Mammalian Genome<\/em><\/strong> 2018, 29: 663-669. (doi: 10.1007\/s00335-018-9773-4)<\/p>\n\n\n\n

2017<\/span><\/h4>\n\n\n\n

Fujihira H., Masahara-Negishi Y., Tamura M.<\/span>, Harada Y., Chengcheng H., Wakana S., Taniguchi N., Kondoh G., Yamashita T., Funakoshi Y. and Suzuki T. Lethality of mice bearing a knockout of the Ngly1-gene is rescued by the additional deletion of the Engase gene. PLoS Genetics<\/em><\/strong> 2017, 13: e1006696 (doi: 10.1371\/journal.pgen.1006696)<\/p>\n\n\n\n

Naruse C., Shibata S., Tamura M.<\/span>, Kawaguchi T., Abe K., Sugihara K., Kato T., Nishiuchi T., Wakana S., Ikawa M. and Asano M. New insights on the role of Jmjd3 and Utx in axial skeletal formation in mice. FASEB Journal<\/em><\/strong> 2017, 31: 2252-2266. (doi:10.1096\/fj.201600642R)<\/p>\n\n\n\n

Kitazawa M., Tamura M.<\/span>, Kaneko-Ishino T. and Ishino F. Severe damage to the placental fetal capillary network causes mid to late fetal lethality and reduction of placental size in Peg11\/Rtl1 KO mice. Genes to Cells<\/em><\/strong> 2017, 22: 174-188. (doi: 10.1111\/gtc.12465)<\/p>\n\n\n\n

Kataoka T., Tamura M.<\/span>, Amano T., Maeno A., Wakana S. and Shiroishi T. Genetic dissection of trabecular bone formation with the B6-MSM consomic mouse strains. G3: Genes, Genomes, Genetics<\/em><\/strong> 2017, 7: 3449-3457. (doi: 10.1534\/g3.117.300213)<\/p>\n\n\n\n

Meehan TF., Conte N., West DB., Jacobsen JO, Mason J., Warren J., Chen C-K., Tudose I., Relac M., Matthews P., Karp N., Santos L., Fiegel T., Ring N., Westerberg H., Greenaway S., Sneddon D., Morgan H., Codner GF., Stewart ME, Brown J, Horner N., The International Mouse Phenotyping Consortium<\/span>, Haendel M., Washington N., Mungall CJ., Reynolds CL., Gallegos J., Gailus-Durner V., Sorg T., Pavlovic G., Bower LB., Moore M., Morse I., Gao X., Tocchini-Valentini GP., Obata Y., Cho SY., Seong JK., Seavitt J., Beaudet AL., Dickinson ME., Herault Y., Wurst W., Hrab\u00e9 de Angelis M., Lloyd KCK., Flenniken AM., Nutter LMJ., Newbigging S., McKerlie C., Justice MJ., Murray SA, Svenson KL., Braun RE., White JK., Bradley A., Flicek P., Wells S., Skarnes WC., Adams DJ., Parkinson H., Mallon AM., Brown SDM., Smedley D. Disease Model Discovery from 3,328 Gene Knockouts by The International Mouse Phenotyping Consortium. Nature Genetics<\/em><\/strong> 2017, 49: 1231-1238. (doi: 10.1038\/ng.3901)<\/p>\n\n\n\n

Bowl MR., Simon MM., Ingham NJ., Greenaway S., Santos L., Cater H., Taylor S., Mason J., Kurbatova N., Pearson S., Bower LR., Clary DA., Meziane H., Reilly P., Minowa O., Kelsey L., The International Mouse Phenotyping Consortium<\/span>, Tocchini-Valentini GP., Gao X., Bradley A., Skarnes WC., Moore M., Beaudet AL., Justice MJ., Seavitt J., Dickinson ME., Wurst W., Hrab\u00e9 de Angelis M., Herault Y., Wakana S., Nutter LMJ., Flenniken AM., McKerlie C., Murray SA., Svenson KL., Braun RE., West DB., Lloyd KCK., Adams DJ., White J., Karp N., Flicek P., Smedley D., Meehan TF., Parkinson HE., Teboul LM., Wells S., Steel KP., Mallon AM., Brown SDM. A large-scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction. Nature Communications<\/em><\/strong> 2017, 8: 886. (doi: 10.1038\/s41467-017-00595-4)<\/p>\n\n\n\n

Karp NA., Mason J., Beaudet AL., Benjamini Y., Bower L., Braun RE., Brown SDM., Chesler EJ., Dickinson ME., Flenniken AM., Fuchs H., Gao X., Guo S., Greenaway S., Heller R., Herault Y., Hrab\u00e9 de Angelis M., Justice MJ., Kurbatova N., Lelliott CJ., Lloyd KCK., Mallon AM., Mank JE., Masuya H., McKerlie C., Meehan TF., Mott RF., Murray SA., Parkinson H., Ramirez-Solis R., Santos L., Seavitt JR., Smedley D., Sorg T., Speak AO., Steel KP., Svenson KL., The International Mouse Phenotyping Consortium<\/span>, Wakana S., West D., Wells S., Westerberg H., Yaacoby S. and White JK. Prevalence of sexual dimorphism in mammalian phenotypic traits. Nature Communications<\/em><\/strong> 2017, 8: 15475. (doi: 10.1038\/ncomms15475)<\/p>\n\n\n\n

Furuse T.<\/span>, Miyake K., Kohda T., Kaneda H., Hirasawa T., Yamada I.<\/span>, Kushida T.<\/span>, Kashimura M., Kobayashi K., Ishino F., Kubota T. and Wakana S. Protein-restricted diet during pregnancy after insemination alters behavioral phenotypes of the progeny. Genes & Nutrition<\/em><\/strong> 2017, 12: 1. (doi: 10.1186\/s12263-016-0550-2)<\/p>\n\n\n\n

Hirose M., Hasegawa A., Mochida K., Matoba S., Hatanaka Y., Inoue K., Goto T., Kaneda H., Yamada I<\/span>., Furuse T.<\/span>, Abe K., Uenoyama Y., Tsukamura H., Wakana S., Honda A. and Ogura A. CRISPR\/Cas9-mediated genome editing in wild-derived mice: generation of tamed wild-derived strains by mutation of the a (nonagouti) gene. Scientific Reports<\/em><\/strong> 2017, 7: 42476. (doi: 10.1038\/srep42476)<\/p>\n\n\n\n

Okumura K., Saito M., Yoshizawa Y., Munakata H., Isogai E., Miura I.<\/span>, Wakana S., Yamaguchi M., Shitara H., Taya C., Karaplis AC., Kominami R. and Wakabayashi Y. The parathyroid hormone regulates skin tumour susceptibility in mice. Scientific Reports<\/em><\/strong> 2017, 7: 11208. (doi: 10.1038\/s41598-017-11561-x)<\/p>\n\n\n\n

Ohnishi T., Miura I.<\/span>, Ohba H., Shimamoto C., Iwayama Y., Wakana S. and Yoshikawa T. A spontaneous and novel Pax3 mutant mouse that models Waardenburg syndrome and neural tube defects. Gene<\/em><\/strong> 2017, 607: 16-22. (doi: 10.1016\/j.gene.2016.12.037)<\/p>\n\n\n\n

2016<\/span><\/h4>\n\n\n\n

Dickinson ME., Flenniken AM., Ji X., Teboul L., Wong MD., White JK., Meehan TF., Weninger WJ., Westerberg H., Adissu H., Baker CN., Bower L., Brown JM., Caddle LB., Chiani F., Clary D., Cleak J., Daly MJ., Denegre JM., Doe B., Edie SM., Fuchs H., Gailus-Durner V., Galli A., Gambadaro A., Gallegos J., Guo S., Horner NR., Hsu Cw., Johnson SJ., Kalaga S., Keith LC., Lanoue L., Lawson TN., Lek M., Mark M., Marschall S., Mason J., McElwee ML., Newbigging S., Nutter LMJ., Peterson KA., Ramirez-Solis R., Rowland DJ., Ryder E., Samocha KE., Seavitt JR., Selloum M., Szoke-Kovacs Z., Tamura M.<\/span>, Trainor AG., Tudose I., Wakana S., Warren J., Wendling O., West DB., Wong L., Yoshiki A., The International Mouse Phenotyping Consortium<\/span>, MacArthur DG., Tocchini-Valentini GP., Gao X., Flicek P., Justice M., Parkinson HE., Moore M., Wells S., Braun RE., Svenson K., Hrab\u00e9 de Angelis M., Herault Y., Mohun T., Mallon AM., Henkelman RM., Brown SD., Adams D., Lloyd KCK., McKerlie C., Beaudet AL., Bucan M. and Murray SA. High-throughput discovery of novel developmental phenotypes. Nature<\/em><\/strong> 2016, 537: 508-514. (doi:10.1038\/nature19356)<\/p>\n\n\n\n

Funato H., Miyoshi C., Fujiyama T., Kanda T., Sato M., Wang Z., Ma J., Nakane S., Tomita J., Ikkyu A., Kakizaki M., Hotta-Hirashima N., Kanno S., Komiya H., Asano F., Honda T., Kim SJ., Harano K., Muramoto H., Yonezawa T., Mizuno S., Miyazaki S., Connor L., Kumar V., Miura I.<\/span>, Suzuki T., Watanabe A., Abe M., Sugiyama F., Takahashi S., Sakimura K., Hayashi Y., Liu Q., Kume K., Wakana S., Takahashi1 JS. and Yanagisawa M. Forward-genetics analysis of sleep in randomly mutagenized mice. Nature<\/em><\/strong> 2016, 539: 378-383. (doi:10.1038\/nature20142)<\/p>\n\n\n\n

Yoshizaki K., Furuse T.<\/span>, Kimura R., Tucci V., Kaneda H., Wakana S. and Osumi N. Paternal Aging Affects Behavior in Pax6 Mutant Mice: A Gene\/Environment Interaction in Understanding Neurodevelopmental Disorders. PLOS ONE<\/em><\/strong> 2016, 11: e0166665. (doi: 10.1371\/journal.pone.0166665)<\/p>\n\n\n\n

Ohba K., Takeda K., Furuse T.<\/span>, Suzuki T., Wakana S., Suzuki T., Yamamoto H. and Shibahara S. Microphthalmia-associated transcription factor ensures the elongation of axons and dendrites in the mouse frontal cortex. Genes to Cells<\/em><\/strong> 2016, 21:1365-1379. (doi: 10.1111\/gtc.12450)<\/p>\n\n\n\n

Liu Y., Maekawa T., Yoshida K., Furuse T.<\/span>, Kaneda H., Wakana S. and Ishii S. ATF7 ablation prevents diet-induced obesity and insulin resistance. Biochem Biophys Res Commun.<\/em><\/strong> 2016, 478: 696-702. (doi: 10.1016\/j.bbrc.2016.08.009)<\/p>\n\n\n\n

Yoshikawa F., Sato Y., Tohyama K., Akagi T., Furuse T.<\/span>, Sadakata T., Tanaka M., Shinoda Y., Hashikawa T., Itohara S., Sano Y., Ghandour MS., Wakana S. and Furuichi T. Mammalian-Specific central myelin protein Opalin is redundant for normal myelination: structural and behavioral assessments. PLOS ONE<\/em><\/strong> 2016, 11: e0166732. (doi: 10.1371\/journal.pone.0166732)<\/p>\n\n\n\n

Yasuda T., Fukada T., Nishida K., Nakayama M., Matsuda M., Miura I.<\/span>, Dainichi T., Fukuda S., Kabashima K., Nakaoka S., Bin BH., Kubo M., Ohno H., Hasegawa T., Ohara O., Koseki H., Wakana S. and Yoshida H. Hyperactivation of JAK1 tyrosine kinase induces stepwise, progressive pruritic dermatitis. Journal of Clinical Investigation<\/em><\/strong> 2016, 126: 2064-76. (doi: 10.1172\/JCI82887)<\/p>\n\n\n\n

Hossain MS., Asano F., Fujiyama T., Miyoshi C., Sato M., Ikkyu A., Kanno S., Hotta N., Kakizaki M., Honda T., Kim SJ., Komiya H., Miura I.<\/span>, Suzuki T., Kobayashi K., Kaneda H., Kumar V., Takahashi JS., Wakana S., Funato H. and Yanagisawa M. Identification of mutations through dominant screening for obesity using C57BL\/6 substrains. Scientific Reports<\/em><\/strong> 2016, 6: 32453. (doi: 10.1038\/srep32453)<\/p>\n\n\n\n

Xie Z., Kitamoto A., Tamura M.<\/span>, Shiroishi T. and Gillies D. High-throughput mouse phenotyping using non-rigid registration and robust principal component analysis. Proceedings of SPIE 9784, Biomedical Imaging<\/em><\/strong> 2016, Image Processing, 978415, e1-e8. (doi: 10.1117\/12.2217155)<\/p>\n\n\n\n

2015<\/span><\/h4>\n\n\n\n

Tamura M.<\/span> and Shiroishi T. GSDM family genes meet autophagy. Biochemical Journal<\/em><\/strong> 2015, 469: e5-e7. (doi: 10.1042\/BJ20150558)<\/p>\n\n\n\n

Xie Z., Liang X., Guo L., Kitamoto A., Tamura M.<\/span>, Shiroishi T. and Gillies D. An automatic classification framework for ventricular septal defects: a pilot study on high-throughput mouse embryo cardiac phenotyping. Journal of Medical Imaging<\/em><\/strong> 2015, 2: 041003. (doi: 10.1117\/1.JMI.2.4.041003)<\/p>\n\n\n\n

Liang X., Xie Z., Tamura M.<\/span>, Shiroishi T., Kitamoto A. Towards high-throughput mouse embryonic phenotyping: a novel approach to classifying ventricular septal defects. Proceedings of SPIE 9413, Medical Imaging<\/em><\/strong> 2015: Image Processing, 94131V, 2015, 66: 1-8. (doi: 10.1117\/12.2081148)<\/p>\n\n\n\n

Irie M., Yoshikawa M., Ono R., Iwafune H., Furuse T.<\/span>, Yamada I.<\/span>, Wakana S., Yamashita Y., Abe T., Ishino F. and Kaneko-Ishino T. Cognitive Function Related to the Sirh11\/Zcchc16 Gene Acquired from an LTR Retrotransposon in Eutherians. PLoS Genetics<\/em><\/strong> 2015, 11: e1005521. (doi: 10.1371\/journal.pgen.1005521)<\/p>\n\n\n\n

Hirawatari K., Hanzawa N., Miura I.<\/span>, Wakana S. and Gotoh H. A Cascade of epistatic interactions regulating teratozoospermia in mice. Mammalian Genome<\/em><\/strong> 2015, 26: 248-56. (doi: 10.1007\/s00335-015-9566-y)<\/p>\n\n\n\n

Uchimura A., Higuchi M., Minakuchi Y., Ohno M., Toyoda A., Fujiyama A., Miura I.<\/span>, Wakana S., Nishino J. and Yagi T. Germline mutation rates and the long-term phenotypic effects of mutation accumulation in wild-type laboratory mice and mutator mice. Genome Research<\/em><\/strong> 2015, 25: 1125-34. (doi: 10.1101\/gr.186148.114)<\/p>\n\n\n\n

Kamimura D., Katsunuma K., Arima Y., Atsumi T., Jiang JJ., Bando H., Meng J., Sabharwal L., Stofkova A., Nishikawa N., Suzuki H., Ogura H., Ueda N., Tsuruoka M., Harada M., Kobayashi J., Hasegawa T., Yoshida H., Koseki H., Miura I.<\/span>, Wakana S., Nishida K., Kitamura H., Fukada T., Hirano T. and Murakami M. KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR. Nature Communications<\/em><\/strong> 2015, 6: 7474. (doi: 10.1038\/ncomms8474)<\/p>\n\n\n\n

Konno D., Kasukawa T., Hashimoto K., Itoh T., Suetsugu T., Miura I.<\/span>, Wakana S., Carninci P. and Matsuzaki F. STAP cells are derived from ES cells. Nature<\/em><\/strong> 2015, 525: E4-5. (doi: 10.1038\/nature15366)<\/p>\n\n\n\n

2014<\/span><\/h4>\n\n\n\n

Tamura M.<\/span>, Amano T. and Shiroishi T. The Hand2 gene dosage effect in developmental defects and human congenital disorders. Curr Top Dev Biol.<\/em><\/strong> 2014, 110: 129-152. (doi: 10.1016\/B978-0-12-405943-6.00003-8)<\/p>\n\n\n\n

Nabeshima Y., Washida M., Tamura M.<\/span>, Yurugi K., Ohnishi M., Maeno A., St-Arnaud S., Shiroishi T., Razzaque MS., Imura A. and Nabeshima Y. Calpain 1 inhibitor, BDA-410 restores a-klotho deficient phenotypes resembling to human aging related syndromes. Scientific Reports<\/em><\/strong> 2014, 4: 5847. (doi: 10.1038\/srep05847)<\/p>\n\n\n\n

Kono H., Tamura M.<\/span>, Osada N., Suzuki H., Abe K., Moriwaki K., Ohta K. and Shiroishi T. Prdm9 polymorphism unveils mouse evolutionary tracks. DNA Research<\/em><\/strong> 2014, 21: 315-326. (doi: 10.1093\/dnares\/dst059)<\/p>\n\n\n\n

Liang X., Xie Z., Kitamoto A., Tamura M.<\/span>, Shiroishi T. and Kotagiri R. A novel atlas-based approach to the detection of mouse embryo ventricular septal defects. Medical image computing and computer-assisted intervention<\/em><\/strong> 2014, 44-45.<\/p>\n\n\n\n

Naruse M., Ono R., Irie M., Nakamura K., Furuse T.<\/span>, Hino T., Oda K., Kashimura M., Yamada I.<\/span>, Wakana S., Yokoyama M., Ishino F. and Kaneko-Ishino T. Sirh7\/Ldoc1 knockout mice exhibit placental P4 overproduction and delayed parturition. Development<\/em><\/strong> 2014, 141: 4763-4771. (doi: 10.1242\/dev.114520)<\/p>\n\n\n\n

Arime Y., Fukumura R., Miura I.<\/span>, Mekada K., Yoshiki A., Wakana S., Gondo Y. and Akiyama K. Effects of background mutations and single nucleotide polymorphisms (SNPs) on the Disc1 L100P behavioral phenotype associated with schizophrenia in mice. Behavioral and Brain Functions<\/em><\/strong> 2014, 10: 45. (doi: 10.1186\/1744-9081-10-45)<\/p>\n\n\n\n

Okumura K., Saito M., Isogai E., Miura I.<\/span>, Wakana S., Kominami R. and Wakabayashi Y. Congenic mapping and allele-specific alteration analysis of Stmm1 locus conferring resistance to early-stage chemically induced skin papillomas. PLOS ONE<\/em><\/strong> 2014, 9: e97201. (doi: 10.1371\/journal.pone.0097201)<\/p>\n\n\n\n

Saito M., Okumura K., Miura I.<\/span>, Wakana S., Kominami R. and Wakabayashi Y. Identification of Stmm3 locus conferring resistance to late-stage chemically induced skin papillomas on mouse chromosome 4 by congenic mapping and allele-specific alteration analysis. Experimental Animals<\/em><\/strong> 2014, 63: 339-348. (doi: 10.1538\/expanim.63.339)<\/p>\n\n\n\n

2013<\/span><\/h4>\n\n\n\n

Tamura M.<\/span>, Hosoya M., Fujita M., Iida T., Amano T., Maeno A., Kataoka T., Otsuka T., Tanaka S, Tomizawa S. and Shiroishi T. Over-dosage of Hand2 causes limb and heart defects in human chromosomal disorder, partial trisomy distal 4q. Human Molecular Genetics<\/em><\/strong> 2013, 22: 2471-2481. (doi: 10.1093\/hmg\/ddt099)<\/p>\n\n\n\n

Tanaka S., Mizushina Y., Kato Y., Tamura M.<\/span> and Shiroishi T. Functional conservation of Gsdma cluster genes specifically duplicated in the mouse genome. G3: Genes, Genomes, Genetics<\/em><\/strong> 2013, 3: 1843-1850. (doi: 10.1534\/g3.113.007393)<\/p>\n\n\n\n

Roy S., Liang X., Kitamoto A., Tamura M.<\/span>, Shiroishi T. and Brown MS. Phenotype detection in morphological mutant mice using deformation features. Medical image computing and computer-assisted intervention<\/em><\/strong> 2013, 16: 437-444.<\/p>\n\n\n\n

Suzuki T., Furuse T.<\/span>, Yamada I.<\/span>, Motegi H., Kozawa Y.<\/span>, Masuya H., Wakana S. Pheno-Pub: a total support system for the publication of mouse phenotypic data on the web. Mammalian Genome<\/em><\/strong> 2013, 24: 473-83. (doi: 10.1007\/s00335-013-9482-y)<\/p>\n\n\n\n

Umemori J., Takao K., Koshimizu H., Hattori S., Furuse T.<\/span>, Wakana S. and Miyakawa T. ENU-mutagenesis mice with a non-synonymous mutation in Grin1 exhibit abnormal anxiety-like behaviors, impaired fear memory, and decreased acoustic startle response. BMC Research Notes<\/em><\/strong> 2013, 6: 203. (doi: 10.1186\/1756-0500-6-203)<\/p>\n\n\n\n

Toki H., Inoue M., Motegi H., Minowa O., Kanda H., Yamamoto N., Ikeda A., Karashima Y., Matsui J., Kaneda H., Miura I.<\/span>, Suzuki T., Wakana S., Masuya H., Gondo Y., Shiroishi T., Akiyama T., Yao R. and Noda T. Novel mouse model for Gardner syndrome generated by a large-scale N-ethyl-N-nitrosourea mutagenesis program. Cancer Science<\/em><\/strong> 2013, 104: 937-944. (doi: 10.1111\/cas.12161)<\/p>\n\n\n\n<\/div>\n","protected":false},"excerpt":{"rendered":"

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